As part of their research, they have put together a set of proposed improvements for Node.js' Web streams implementation that will eliminate promises in certain code paths which can yield a significant performance boost up to 10x faster, which only goes to prove the point: promises, while useful, add significant overhead. As one of the core maintainers of Node.js, I am looking forward to helping Malte and the folks at Vercel get their proposed improvements landed!
Iran conflict: Iraq’s crude production on cusp of collapse
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In 2006, 454 collaborated with Swedish paleogeneticist Svante Pääbo to sequence the first million base pairs of the Neanderthal genome; the project would be completed four years later, albeit with some help from Illumina sequencing. Illumina and other subsequent NGS technologies rendered pyrosequencing non-competitive, and in 2013, 454 was shut down by Roche, which had acquired it six years earlier. The technology is still used today for some applications, but most importantly, it was the first commercially viable alternative to Sanger sequencing, and the first sequencing method that could be fully automated because it didn’t rely on gels or other tedious steps.